Morphological MRI features as prognostic indicators in brain metastases.

ABSTRACT:

Background

Stereotactic radiotherapy is the preferred treatment for managing patients with fewer than five brain metastases (BMs). However, some lesions recur after irradiation. The purpose of this study was to identify patients who are at a higher risk of failure, which can help in adjusting treatments and preventing recurrence.

Methods

In this retrospective multicenter study, we analyzed the predictive significance of a set of interpretable morphological features derived from contrast-enhanced (CE) T1-weighted MR images as imaging biomarkers using Kaplan-Meier analysis. The feature sets studied included the total and necrotic volumes, the surface regularity and the CE rim width. Additionally, we evaluated other nonmorphological variables and performed multivariate Cox anal

SUBMITTER: Ocana-Tienda B 

PROVIDER: S-EPMC11334491 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature