Optimizing microbioreactor cultivation strategies for Trichoderma reesei: from batch to fed-batch operations.

ABSTRACT:

Background

Filamentous fungi have long been recognized for their exceptional enzyme production capabilities. Among these, Trichoderma reesei has emerged as a key producer of various industrially relevant enzymes and is particularly known for the production of cellulases. Despite the availability of advanced gene editing techniques for T. reesei, the cultivation and characterization of resulting strain libraries remain challenging, necessitating well-defined and controlled conditions with higher throughput. Small-scale cultivation devices are popular for screening bacterial strain libraries. However, their current use for filamentous fungi is limited due to their complex morphology.

Results

This study addresses this research gap through the development of a batch cultivation

SUBMITTER: Rohr K 

PROVIDER: S-EPMC11334512 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature