Production of structurally diverse sphingolipids by anaerobic marine bacteria in the euxinic Black Sea water column.

ABSTRACT: Microbial lipids, used as taxonomic markers and physiological indicators, have mainly been studied through cultivation. However, this approach is limited due to the scarcity of cultures of environmental microbes, thereby restricting insights into the diversity of lipids and their ecological roles. Addressing this limitation, here we apply metalipidomics combined with metagenomics in the Black Sea, classifying and tentatively identifying 1623 lipid-like species across 18 lipid classes. We discovered over 200 novel, abundant, and structurally diverse sphingolipids in euxinic waters, including unique 1-deoxysphingolipids with long-chain fatty acids and sulfur-containing groups. Sphingolipids were thought to be rare in bacteria and their molecular and ecological functions in bacterial membrane

SUBMITTER: Ding S 

PROVIDER: S-EPMC11334938 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature