Effect of H₂O₂-V_C degradation on structural characteristics and immunomodulatory activity of larch arabinogalactan.

ABSTRACT: The arabinogalactan in the representative softwood biomass of larch was degraded using an environmentally friendly hydrogen peroxide and vitamin C (H₂O₂-V_C) system to improve its immunomodulatory activity. Through the H₂O₂-V_C degradation mechanism, hydroxyl radicals are generated, which then target the hydrogen atoms within polysaccharides, resulting in the breaking of glycosidic bonds. Given the impact of oxidative degradation on polysaccharides, we identified three specific arabinogalactan degradation products distinguished by their arabinosyl side chain compositions. The primary structures of the degradation products were investigated using Fourier-transform infrared spectroscopy and nuclear magnetic resonance spectroscop

SUBMITTER: Qi H 

PROVIDER: S-EPMC11335654 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature