Late dysfunction of a mechanical aortic valve after long-term low molecular weight heparin therapy: a case report.

ABSTRACT:

Background

To date, vitamin K anticoagulants are the only recommended long-term therapy for mechanical heart valves. Bleeding episodes, thromboembolic events, and international normalized ratio monitoring are difficult and prevalent complications for these patients. This report reflects the late mechanical aortic valve dysfunction after long-term low molecular weight heparin therapy.

Case summary

A 66-year-old male patient underwent mechanical aortic valve replacement in 2007. He was administered therapeutic doses of enoxaparin for nearly 12 years due to warfarin-related bleeding complications and labile international normalized ratios. However, he experienced multiple cardiovascular and cerebrovascular thromboembolic events, including an anterolateral ST-elevation myocardia

SUBMITTER: Mon A 

PROVIDER: S-EPMC11337000 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature