Naloxone and Patient Outcomes in Out-of-Hospital Cardiac Arrests in California.

ABSTRACT:

Importance

The incidence of opioid-associated out-of-hospital cardiac arrest (OA-OHCA) has grown from less than 1% of OHCA in 2000 to between 7% and 14% of OHCA in recent years; American Heart Association (AHA) protocols suggest that emergency medical service (EMS) clinicians consider naloxone in OA-OHCA. However, it is unknown whether naloxone improves survival in these patients or in patients with undifferentiated OHCA.

Objective

To evaluate the association of naloxone with clinical outcomes in patients with undifferentiated OHCA.

Design, setting, and participants

Retrospective cohort study of EMS-treated patients aged 18 or older who received EMS treatment for nontraumatic OHCA in 3 Northern California counties between 2015 and 2023. Data were analyzed using propen

SUBMITTER: Dillon DG 

PROVIDER: S-EPMC11337064 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature