Association of oral fungal profiles with health status and bacterial composition in elderly adults receiving community support and home care service.

ABSTRACT: Fungi compose a minority but a common component of normal oral microbiota and contribute to oral and systemic health by interacting with bacterial inhabitants. This study investigated the relationship of oral fungal profiles to health status and bacterial profiles of 159 elderly adults receiving community support and home care services. Fungal and bacterial densities and compositions were determined based on the fungal ribosomal internal transcribed spacer region and bacterial 16S rRNA gene amplicon analyses, respectively. The total fungal density of 87 individuals exceeded 5,000 copies, and their microbiota was characterized by significantly less dense bacterial populations and lower relative abundances of oral health-associated taxa, such as Neisseria perflava and Porphyromonas

SUBMITTER: Asakawa M 

PROVIDER: S-EPMC11337817 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature