Mar1, a high mobility group box protein, regulates <i>n</i>-alkane adsorption and cell morphology of the dimorphic yeast <i>Yarrowia lipolytica</i>.

ABSTRACT: The dimorphic yeast Yarrowia lipolytica possesses an excellent ability to utilize n-alkane as a sole carbon and energy source. Although there are detailed studies on the enzymes that catalyze the reactions in the metabolic processes of n-alkane in Y. lipolytica, the molecular mechanism underlying the incorporation of n-alkane into the cells remains to be elucidated. Because Y. lipolytica adsorbs n-alkane, we postulated that Y. lipolytica incorporates n-alkane through direct interaction with it. We isolated and characterized mutants defective in adsorption to n-hexadecane. One of the mutants harbored a nonsense mutation in MAR1 (Morphology and n-alkane Adsorption Regulator 1) encoding a

SUBMITTER: Kimura-Ishimaru C 

PROVIDER: S-EPMC11337826 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature