Endpoints and outcomes for localized scleroderma/morphea: a scoping literature review.

ABSTRACT: Current treatment for localized scleroderma (LS) has been shown to halt disease activity, but little is still known about patient experiences with these treatments, nor is there consensus about optimal measurement strategies for future clinical trials. Conduct a scoping review of the literature for the types of outcomes and measures (i.e. clinician-, patient-, and caregiver-reported) utilized in published treatment studies of LS. Online databases were searched for articles related to the evaluation of treatment efficacy in LS with a special focus on pediatrics. Of the 168 studies, the most common outcomes used were cutaneous disease activity and damage measured via clinician-reported assessments. The most frequently cited measure was the Localized Scleroderma Cutaneous Assessment Tool (LoS

SUBMITTER: Hernandez A 

PROVIDER: S-EPMC11337887 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature