Impact of wheat sensitization on wheeze and T2 phenotypes in general population of children.

ABSTRACT:

Background

The association between sensitization to specific aeroallergens and outcomes in patients with asthma is well researched; however, the association between childhood-onset wheeze/asthma and sensitization to various aeroallergens and food allergens in the general pediatric population remains poorly understood.

Objective

We sought to investigate the association between sensitization to common aeroallergens and food allergens with wheeze and type 2 (T2) inflammation in the general pediatric population.

Methods

Specific IgEs against 9 aeroallergens and 4 food allergens were measured in the prospective Hokkaido birth cohort of 428 school-age children (age ∼10 years). Wheeze and other allergic symptoms were assessed using the International Study of Asthma and Aller

SUBMITTER: Goudarzi H 

PROVIDER: S-EPMC11338083 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature