Delayed time to radiation and overall survival in Merkel cell carcinoma.

ABSTRACT:

Background

Clinically localized Merkel cell carcinoma (MCC) is commonly treated with surgical excision and radiotherapy. The relationship between time to adjuvant radiotherapy and overall survival (OS) remains understudied.

Methods

This retrospective study used data from the National Cancer Database (2006-2019). Patients with clinically localized MCC who received surgical excision and adjuvant radiotherapy were included. Multivariate regressions were used to account for various patient and tumor factors. The primary outcome was 5-year OS, and the secondary outcome was time from diagnosis to adjuvant radiation (TTR).

Results

Of the 1965 patients included, most were male (n = 1242, 63.2%) and white (n = 1915, 97.5%), and the median age was 74 years (interquartile range

SUBMITTER: Ma KL 

PROVIDER: S-EPMC11338135 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature