Antidepressant class and concurrent rTMS outcomes in major depressive disorder: a systematic review and meta-analysis.

ABSTRACT:

Background

Repetitive transcranial magnetic stimulation (rTMS) is frequently used as an adjunctive treatment with antidepressants for depression. We aimed to evaluate the clinical efficacy and safety of antidepressant classes when administered concurrently with rTMS for the management of major depressive disorder (MDD).

Methods

In this systematic review and meta-analysis, MEDLINE, Embase, PsycINFO, and the Cochrane Library were searched from inception to April 12th 2024 for terms relating to medication, depression, and rTMS and appraised by 2 independent screeners. All randomized clinical trials that prospectively evaluated a specific antidepressant adjunctively with sham rTMS as a control in MDD were included. The study was registered with PROSPERO (CRD42023418435). The pri

SUBMITTER: Zaidi A 

PROVIDER: S-EPMC11338161 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature