Microstructural Properties of the Cerebellar Peduncles in Children With Developmental Language Disorder.

ABSTRACT: Children with developmental language disorder (DLD) struggle to learn their native language for no apparent reason. While research on the neurobiological underpinnings of the disorder has focused on the role of corticostriatal systems, little is known about the role of the cerebellum in DLD. Corticocerebellar circuits might be involved in the disorder as they contribute to complex sensorimotor skill learning, including the acquisition of spoken language. Here, we used diffusion-weighted imaging data from 77 typically developing and 54 children with DLD and performed probabilistic tractography to identify the cerebellum's white matter tracts: the inferior, middle, and superior cerebellar peduncles. Children with DLD showed lower fractional anisotropy (FA) in the inferior cerebellar peduncle

SUBMITTER: Asaridou SS 

PROVIDER: S-EPMC11338306 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature