Derivation and assessment of a sex-specific fetal growth standard.

ABSTRACT:

Purpose

To derive a prescriptive sex-specific fetal growth standard and assess clinical management and outcomes according to sex-specific growth status.

Materials and methods

This was a secondary analysis of the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be (nuMoM2b), a prospective observational study of 10,038 nulliparas from eight U.S. centers who underwent ultrasounds at 14-20 and 22-29 weeks with outcomes ascertained after delivery. From these, we selected a nested cohort of lower risk participants (excluded those with chronic hypertension, pre-gestational diabetes, suspected aneuploidy, and preterm delivery) to derive a sex-specific equation for expected fetal growth using fetal weights by ultrasound and at birth. We compared the male-female discrepancy

SUBMITTER: Blue NR 

PROVIDER: S-EPMC11338582 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature