Ingestion of the Non-Nutritive Sweetener Erythritol, but Not Glucose, Enhances Platelet Reactivity and Thrombosis Potential in Healthy Volunteers-Brief Report.

ABSTRACT:

Background

Although artificial and non-nutritive sweeteners are widely used and generally recognized as safe by the US and European Union regulatory agencies, there have been no clinical trials to assess either long-term cardiovascular disease risks or short-term cardiovascular disease-relevant phenotypes. Recent studies report that fasting plasma levels of erythritol, a commonly used sweetener, are clinically associated with heightened incident cardiovascular disease risks and enhance thrombosis potential in vitro and in animal models. Effects of dietary erythritol on thrombosis phenotypes in humans have not been examined.

Methods

Using a prospective interventional study design, we tested the impact of erythritol or glucose consumption on multiple indices of stimulus-depend

SUBMITTER: Witkowski M 

PROVIDER: S-EPMC11338701 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature