Generalizable Links Between Borderline Personality Traits and Functional Connectivity.

ABSTRACT:

Background

Symptoms of borderline personality disorder (BPD) often manifest during adolescence, but the underlying relationship between these debilitating symptoms and the development of functional brain networks is not well understood. Here, we aimed to investigate how multivariate patterns of functional connectivity are associated with borderline personality traits in large samples of young adults and adolescents.

Methods

We used functional magnetic resonance imaging data from young adults and adolescents from the HCP-YA (Human Connectome Project Young Adult) (n = 870, ages 22-37 years, 457 female) and the HCP-D (Human Connectome Project Development) (n = 223, ages 16-21 years, 121 female). A previously validated BPD proxy score was derived from the NEO Five-Factor Invento

SUBMITTER: Shafiei G 

PROVIDER: S-EPMC11338739 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature