Two-Year Progression of Dry Eye Disease in Dry Eye Assessment and Management Study.

ABSTRACT:

Purpose

The purpose of this study was to evaluate the progression of dry eye disease (DED) symptoms and signs over 2 years through a secondary analysis of data collected from the Dry Eye Assessment and Management study.

Methods

Participants who were assigned to omega-3 fatty acid in the first year were rerandomized in the second year to either continue with omega-3 fatty acid or switch to placebo. At baseline, 3, 6, 12, 18, and 24 months, DED symptoms were evaluated by using the Ocular Surface Disease Index and the Brief Ocular Discomfort Index (BODI). DED signs were assessed using conjunctival staining, corneal staining, tear break-up time, Schirmer testing, and keratography measures. Medication usage was documented at each visit. Because the treatment and placebo groups di

SUBMITTER: Lee DC 

PROVIDER: S-EPMC11339235 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature