Neural correlates of proactive avoidance deficits and alcohol use motives in problem drinking.

ABSTRACT: Physical pain and negative emotions represent two distinct drinking motives that contribute to harmful alcohol use. Proactive avoidance, in contrast, can reduce consumption in response to these motives but appears to be impaired in those with problem drinking. Despite such evidence, proactive avoidance and its underlying neural deficits have not been assessed experimentally. How these deficits inter-relate with drinking motives to influence alcohol use also remains unclear. The current study leveraged neuroimaging data in forty-one problem and forty-one social drinkers who performed a probabilistic learning go/nogo task featuring proactive avoidance of painful outcomes. We identified the brain responses to proactive avoidance and contrasted the neural correlates of drinking to avoid negati

SUBMITTER: Le TM 

PROVIDER: S-EPMC11339324 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature