Large language models facilitate the generation of electronic health record phenotyping algorithms.

ABSTRACT:

Objectives

Phenotyping is a core task in observational health research utilizing electronic health records (EHRs). Developing an accurate algorithm demands substantial input from domain experts, involving extensive literature review and evidence synthesis. This burdensome process limits scalability and delays knowledge discovery. We investigate the potential for leveraging large language models (LLMs) to enhance the efficiency of EHR phenotyping by generating high-quality algorithm drafts.

Materials and methods

We prompted four LLMs-GPT-4 and GPT-3.5 of ChatGPT, Claude 2, and Bard-in October 2023, asking them to generate executable phenotyping algorithms in the form of SQL queries adhering to a common data model (CDM) for three phenotypes (ie, type 2 diabetes mellitus, demen

SUBMITTER: Yan C 

PROVIDER: S-EPMC11339509 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature