Ontology highlight
ABSTRACT:
SUBMITTER: Hu X
PROVIDER: S-EPMC11339954 | biostudies-literature | 2024 Aug
REPOSITORIES: biostudies-literature
Chemical science 20240722 33
Distal biaxial atropisomers are typical structures in chiral catalysts and ligands and offer a wide variety of applications in biology and materials technology, but the development of efficient synthesis of these valuable scaffolds is still in great demand. Herein, we describe a highly efficient iridium catalyzed asymmetric C-H alkylation reaction that provides a range of new distal biaxial atropisomers with excellent yields (up to 99%) and stereoselectivity (up to 99% ee and essentially one iso ...[more]