Helicity control of a polyaromatic coordination capsule through stereoselective CH-π interactions.

ABSTRACT: Although square-planar ML₄ units are essential building blocks for coordination cages and capsules, the non-covalent control of the chirality and helicity of the resultant nanostructures is quite difficult. Here we report the helicity control of an M₂L₄ polyaromatic capsule, formed from metal ions with square-planar coordination geometry and bent bispyridine ligands, through stereoselective CH-π interactions with monosaccharide derivatives. Thanks to host-guest CH-π multi-interactions, one molecule of various permethylated monosaccharides is quantitatively bound by the capsule in water (K _a up to >10⁸ M^-1). In the polyaromatic cavity, among them, the selective binding of a β-glucose derivative (>80 : 20 ratio) is demo

SUBMITTER: Kishida N 

PROVIDER: S-EPMC11339976 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature