Exploring the role of non-coding RNAs in atrial septal defect pathogenesis: A systematic review.

ABSTRACT:

Background

Extensive research has recognized the significant roles of non-coding RNAs (ncRNAs) in various cellular pathophysiological processes and their association with diverse diseases, including atrial septal defect (ASD), one of the most prevalent congenital heart diseases. This systematic review aims to explore the intricate involvement and significance of ncRNAs in the pathogenesis and progression of ASD.

Methods

Four databases (PubMed, Embase, Scopus, and the Web of Science) were searched systematically up to June 19, 2023, with no year restriction. The risk of bias assessment was evaluated using the Newcastle-Ottawa scale.

Results

The present systematic review included thirteen studies with a collective study population of 874 individuals diagnosed with ASD,

SUBMITTER: AmiRsardari Z 

PROVIDER: S-EPMC11340980 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature