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Assessing pyrethroid resistance in Aedes aegypti from Cordoba Colombia: Implications of kdr mutations.


ABSTRACT: Resistance to insecticides is one of the great challenges that vector control programs must face. The constant use of pyrethroid-type insecticides worldwide has caused selection pressure in populations of the Aedes aegypti vector, which has promoted the emergence of resistant populations. The resistance mechanism to pyrethroid insecticides most studied to date is target-site mutations that desensitize the voltage-gated sodium channel (VGSC) of the insect to the action of pyrethroids. In the present study, susceptibility to the pyrethroid insecticides permethrin, lambda-cyhalothrin, and deltamethrin was evaluated in fourteen populations from the department of Córdoba, Colombia. The CDC bottle bioassay and WHO tube methods were used. Additionally, the frequencies of the F1534C, V1016I, and V

SUBMITTER: Atencia-Pineda MC 

PROVIDER: S-EPMC11340990 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature