CagA toxin and risk of Helicobacter pylori-infected gastric phenotype: A meta-analysis of observational studies.

ABSTRACT:

Background

Helicobacter pylori (H. pylori) is frequently associated with non-cardia type gastric cancer, and it is designated as a group I carcinogen. This study aimed to systematically review and meta-analyze the evidence on the prevalence of CagA status in people with gastric disorders in the Indo-Pacific region, and to examine the association of CagA positive in the risk of gastric disorders. This study focused on the Indo-Pacific region owing to the high disability adjusted life-years related to these disorders, the accessibility of efficient treatments for this common bacterial infection, and the varying standard of care for these disorders, particularly among the elderly population in the region.

Methods

Relevant studies were identified in the health-related electronic

SUBMITTER: Naing C 

PROVIDER: S-EPMC11341061 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature