Bioactive plant waste components targeting oral bacterial pathogens as a promising strategy for biofilm eradication.

ABSTRACT: The significance of this study lies in its exploration of bioactive plant extracts as a promising avenue for combating oral bacterial pathogens, offering a novel strategy for biofilm eradication that could potentially revolutionize oral health treatments. Oral bacterial infections are common in diabetic patients; however, due to the development of resistance, treatment options are limited. Considering the excellent antimicrobial properties of phenolic compounds, we investigated them against isolated oral pathogens using in silico and in vitro models. We performed antibiogram studies and minimum inhibitory concentration (MIC), antibiofilm, and antiquorum sensing activities covering phenolic compounds. Bacterial strains were isolated from female diabetic patients and identified

SUBMITTER: Mashal S 

PROVIDER: S-EPMC11341444 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature