Expert perspectives on ECCO₂R for acute hypoxemic respiratory failure: consensus of a 2022 European roundtable meeting.

ABSTRACT:

Background

By controlling hypercapnia, respiratory acidosis, and associated consequences, extracorporeal CO₂ removal (ECCO₂R) has the potential to facilitate ultra-protective lung ventilation (UPLV) strategies and to decrease injury from mechanical ventilation. We convened a meeting of European intensivists and nephrologists and used a modified Delphi process to provide updated insights into the role of ECCO₂R in acute respiratory distress syndrome (ARDS) and to identify recommendations for a future randomized controlled trial.

Results

The group agreed that lung protective ventilation and UPLV should have distinct definitions, with UPLV primarily defined by a tidal volume (V_T) of 4-6 mL/kg predicted body weight with a driving press

SUBMITTER: Combes A 

PROVIDER: S-EPMC11341504 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature