Likelihood-of-harm/help of microsurgery compared to radiosurgery in large vestibular schwannoma.

ABSTRACT:

Purpose

It has been shown that in large vestibular schwannomas (VS), radiosurgery (SRS) is inferior with respect to tumor control compared to microsurgical resection (SURGERY). However, SURGERY poses a significantly higher risk of facial-function deterioration (FFD). The aim of this study was to illustrate the effectiveness in terms of number-needed-to-treat/operate (NNO), number-needed-to-harm (NNH), and likelihood-of-harm/help (LHH) by comparing both treatment modalities in large VS.

Methods

This was a retrospective, dual-center cohort study. Tumor size was classified by Hannover Classification. Absolute risk reduction and risk increase were used to derive additional estimates of treatment effectiveness, namely NNO and NNH. LHH was then calculated by a quotient of NNH/NNO

SUBMITTER: Wang SS 

PROVIDER: S-EPMC11341602 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature