Development and validation of a neoadjuvant chemotherapy pathological complete remission model based on Reg IV expression in breast cancer tissues: a clinical retrospective study.

ABSTRACT:

Objective

To develop and authenticate a neoadjuvant chemotherapy (NACT) pathological complete remission (pCR) model based on the expression of Reg IV within breast cancer tissues with the objective to provide clinical guidance for precise interventions.

Method

Data relating to 104 patients undergoing NACT were collected. Variables derived from clinical information and pathological characteristics of patients were screened through logistic regression, random forest, and Xgboost methods to formulate predictive models. The validation and comparative assessment of these models were conducted to identify the optimal model, which was then visualized and tested.

Result

Following the screening of variables and the establishment of multiple models based on these variables, com

SUBMITTER: Wei JF 

PROVIDER: S-EPMC11341653 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature