Dataset Information

Detection of microplastics in human tissues and organs: A scoping review.

ABSTRACT:

Background

Research on microplastics has largely focused on the environment and marine organisms until recently. A growing body of evidence has detected microplastics in human organs and tissues, with their exact entry routes being unclear and their potential health effects remain unknown. This scoping review aimed to characterise microplastics in human tissues and organs, examine their entry routes and addressing gaps in research analytical techniques.

Methods

Eligibility criteria included English language full text articles, in-vivo human studies only, and searching the databases using pre-defined terms. We based our analysis and reporting on the PRISMA guideline and examined the quality of evidence using the risk of bias assessment tool.

Results

Of 3616 articles screened, 223 evaluated and 26 were eventually included in this review. Nine were high risk for bias, three were unclear risk and the rest low risk for bias. Microplastics were detected in 8/12 human organ systems including cardiovascular, digestive, endocrine, integumentary, lymphatic, respiratory, reproductive and urinary. Microplastics were also observed in other human biological samples such as breastmilk, meconium, semen, stool, sputum and urine. Microplastics can be characterised based on shape, colours, and polymer type. Potential entry routes into human included atmospheric inhalation and ingestion through food and water. The extraction techniques for analysis of microplastics in human tissues vary significantly, each offering distinct advantages and limitations.

Conclusions

Microplastics are commonly detected in human tissues and organs, with distinct characteristics and entry routes, and variable analytical techniques exist.

SUBMITTER: Roslan NS

PROVIDER: S-EPMC11342020 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature

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Publications

Detection of microplastics in human tissues and organs: A scoping review.

Roslan Nur Sakinah NS Lee Yeong Yeh YY Ibrahim Yusof Shuaib YS Tuan Anuar Sabiqah S Yusof Ku Mohd Kalkausar Ku KMKK Lai Lisa Ann LA Brentnall Teresa T

Journal of global health 20240823

<h4>Background</h4>Research on microplastics has largely focused on the environment and marine organisms until recently. A growing body of evidence has detected microplastics in human organs and tissues, with their exact entry routes being unclear and their potential health effects remain unknown. This scoping review aimed to characterise microplastics in human tissues and organs, examine their entry routes and addressing gaps in research analytical techniques.<h4>Methods</h4>Eligibility criteri ...[more]

PMID: 39175335

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Dataset Information

Detection of microplastics in human tissues and organs: A scoping review.

Background

Methods

Results

Conclusions

Publications

Detection of microplastics in human tissues and organs: A scoping review.

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