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Blood-based biomemristor for hyperglycemia and hyperlipidemia monitoring.


ABSTRACT: Thanks to its structural characteristics and signal patterns similar to those of human brain synapses, memristors are widely believed to be applicable for neuromorphic computing. However, to our knowledge, memristors have not been effectively applied in the biomedical field, especially in disease diagnosis and health monitoring. In this work, a blood-based biomemristor was prepared for in vitro detection of hyperglycemia and hyperlipidemia. It was found that the device exhibits excellent resistance switching (RS) behavior at lower voltage biases. Through mechanism analysis, it has been confirmed that the RS behavior is driven by Ohmic conduction and ion rearrangement. Furthermore, the hyperglycemia and hyperlipidemia detection devices were constructed for the first time based on memristor logic circuits, and circuit simulations were conducted. These results confirm the feasibility of blood-based biomemristors in detecting hyperglycemia and hyperlipidemia, providing new prospects for the important application of memristors in the biomedical field.

SUBMITTER: Gao K 

PROVIDER: S-EPMC11342282 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature

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Blood-based biomemristor for hyperglycemia and hyperlipidemia monitoring.

Gao Kaikai K   Sun Bai B   Zhou Guangdong G   Cao Zelin Z   Xiang Linbiao L   Yu Jiawei J   Wang Ruixin R   Yao Yingmin Y   Lin Fulai F   Li Zhuoqun Z   Ren Fenggang F   Lv Yi Y   Lu Qiang Q  

Materials today. Bio 20240729


Thanks to its structural characteristics and signal patterns similar to those of human brain synapses, memristors are widely believed to be applicable for neuromorphic computing. However, to our knowledge, memristors have not been effectively applied in the biomedical field, especially in disease diagnosis and health monitoring. In this work, a blood-based biomemristor was prepared for in vitro detection of hyperglycemia and hyperlipidemia. It was found that the device exhibits excellent resista  ...[more]

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