Genetic diversity and cross-species transmissibility of bat-associated picornaviruses from Spain.

ABSTRACT:

Background

Emerging zoonotic diseases arise from cross-species transmission events between wild or domesticated animals and humans, with bats being one of the major reservoirs of zoonotic viruses. Viral metagenomics has led to the discovery of many viruses, but efforts have mainly been focused on some areas of the world and on certain viral families.

Methods

We set out to describe full-length genomes of new picorna-like viruses by collecting feces from hundreds of bats captured in different regions of Spain. Viral sequences were obtained by high-throughput Illumina sequencing and analyzed phylogenetically to classify them in the context of known viruses. Linear discriminant analysis (LDA) was performed to infer likely hosts based on genome composition.

Results

We foun

SUBMITTER: Carrascosa-Saez M 

PROVIDER: S-EPMC11342490 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature