Blood coagulation in Prediabetes clusters-impact on all-cause mortality in individuals undergoing coronary angiography.

ABSTRACT:

Background

Metabolic clusters can stratify subgroups of individuals at risk for type 2 diabetes mellitus and related complications. Since obesity and insulin resistance are closely linked to alterations in hemostasis, we investigated the association between plasmatic coagulation and metabolic clusters including the impact on survival.

Methods

Utilizing data from the Ludwigshafen Risk and Cardiovascular Health (LURIC) study, we assigned 917 participants without diabetes to prediabetes clusters, using oGTT-derived glucose and insulin, high-density lipoprotein cholesterol, triglycerides, and anthropometric data. We performed a comprehensive analysis of plasmatic coagulation parameters and analyzed their associations with mortality using proportional hazards models. Mediation an

SUBMITTER: Horber S 

PROVIDER: S-EPMC11342575 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature