Post-eclosion growth in the <i>Drosophila</i> Ejaculatory Duct is driven by Juvenile Hormone signaling and is essential for male fertility.

ABSTRACT: The Drosophila Ejaculatory duct (ED) is a secretory tissue of the somatic male reproductive system. The ED is involved in the secretion of seminal fluid components and ED-specific antimicrobial peptides that aid in fertility and the female post-mating response. The ED is composed of secretory epithelial cells surrounded by a layer of innervated contractile muscle. The ED grows in young adult males during the first 24h post-eclosion, but the cell cycle status of the ED secretory cells and the role of post-eclosion ED growth have been unexplored. Here, we show that secretory cells of the adult Drosophila ED undergo variant cell cycles lacking mitosis called the endocycle, that lead to an increase in the cell and organ size of the ED post eclosion. The cells largely exit the end

SUBMITTER: Ramesh NA 

PROVIDER: S-EPMC11343125 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature