Postnatal growth and neurodevelopment at 2 years' corrected age in extremely low birthweight infants.

ABSTRACT:

Background

Faltering postnatal growth in preterm babies is associated with adverse neurodevelopment. However, which growth reference is most helpful for predicting neurodevelopment is unknown. We examined associations between faltering growth and developmental delay in extremely low birthweight (ELBW) infants.

Methods

We categorized faltering growth (z-score decrease ≥0.8 for weight/length, >1 for head circumference) between birth, 4 weeks, 36 weeks' postmenstrual age and 2 years' corrected age using fetal (Fenton, UK-WHO and Olsen) and healthy preterm (INTERGROWTH-21st) references. Associations between faltering growth and developmental delay were examined using binary logistic regression and area under the receiver operating curve (AUC).

Results

In 327 infants, Olse

SUBMITTER: Nyakotey DA 

PROVIDER: S-EPMC11343699 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature