Associations between human milk oligosaccharides and infant growth in a Bangladeshi mother-infant cohort.

ABSTRACT:

Background

We aimed to estimate associations between human milk oligosaccharides (HMOs) and infant growth (length-for-age (LAZ) and weight-for-length (WLZ) z-scores) at 12 months postnatal age.

Methods

In this secondary analysis of data from a maternal vitamin D trial in Dhaka, Bangladesh (N = 192), absolute concentrations of HMOs were measured in 13 ± 1 week(s) postpartum milk samples, infant anthropometric measurements were obtained soon after birth and at 12 months postpartum, and infant feeding was classified during 6 months postpartum. Associations between individual HMOs or HMO groups and LAZ or WLZ were estimated by multivariable linear regression adjusting for infant feeding pattern, maternal secretor status, and other potential confounders.

Results

The concen

SUBMITTER: Loutet MG 

PROVIDER: S-EPMC11343707 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature