Caesarean section and risk of type 1 diabetes.

ABSTRACT:

Aims/hypothesis

Delivery by Caesarean section continues to rise globally and has been associated with the risk of developing type 1 diabetes and the rate of progression from pre-symptomatic stage 1 or 2 type 1 diabetes to symptomatic stage 3 disease. The aim of this study was to examine the association between Caesarean delivery and progression to stage 3 type 1 diabetes in children with pre-symptomatic early-stage type 1 diabetes.

Methods

Caesarean section was examined in 8135 children from the TEDDY study who had an increased genetic risk for type 1 diabetes and were followed from birth for the development of islet autoantibodies and type 1 diabetes.

Results

The likelihood of delivery by Caesarean section was higher in children born to mothers with type 1 diabetes (

SUBMITTER: Singh T 

PROVIDER: S-EPMC11343945 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature