Ontology highlight
ABSTRACT:
SUBMITTER: Gavenas J
PROVIDER: S-EPMC11344096 | biostudies-literature | 2024 Aug
REPOSITORIES: biostudies-literature
Gavenas Jake J Rutishauser Ueli U Schurger Aaron A Maoz Uri U
Nature communications 20240824 1
The capacity to initiate actions endogenously is critical for goal-directed behavior. Spontaneous voluntary actions are typically preceded by slow-ramping activity in medial frontal cortex that begins around two seconds before movement, which may reflect spontaneous fluctuations that influence action timing. However, the mechanisms by which these slow ramping signals emerge from single-neuron and network dynamics remain poorly understood. Here, we developed a spiking neural-network model that pr ...[more]