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Assessing oral and toothbrush microbial profiles among high-altitude individuals with and without periodontal disease: a case-control study.


ABSTRACT:

Background

Periodontitis is the sixth-most common disease worldwide. The oral microbiome composition and its association with Periodontal disease (PD) have been largely explored; however, limited studies have explored the microbial profiles of both oral and toothbrushes in patients with PD. Thus, this study aimed to ascertain the oral and toothbrushes microbial composition in high-altitude populations, hypothesizing that their correlation with periodontal health would differ from those at lower altitudes, potentially indicating links between environmental factors, microbial colonization patterns, and periodontal health in distinct geographic contexts.

Methods

In the present study, we enrolled 35 individuals including 21 healthy and 14 diagnosed with PD from the Lhasa region

SUBMITTER: Lei S 

PROVIDER: S-EPMC11344349 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature