The Global Burden of Alcohol-associated Cirrhosis and Cancer in Young and Middle-aged Adults.

ABSTRACT: Alcohol is a substance that impacts premature mortality and morbidity.¹ The liver is invariably subjected to the impact of alcohol, which can result in cirrhosis and cancer. Alcohol also has detrimental effects that extend beyond the liver. While traditionally associated with advanced age, emerging data reported a rising burden of cancers and alcohol-associated liver disease in the young.^1-3 Thus, the primary objective was to evaluate the trend of alcohol-associated cirrhosis and cancer in young and middle-aged adults (aged 15-49) utilizing the Global Burden of Disease Study (GBD) 2019.⁴ We chose the age group less than 50 years old based on the definition of early-onset cancer and the inherent selection of the age group in the GBD database.^4-6 T

SUBMITTER: Danpanichkul P 

PROVIDER: S-EPMC11344661 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature