Characteristics and Impact of Randomized Trials on Drugs or Devices in Cardiovascular Medicine.

ABSTRACT:

Introduction

Clinical trials, essential for medical advancement, vary significantly in methodology and regulatory pathways depending on the type of therapeutic intervention (i.e., drugs or devices). This study aimed to determine whether the drug or device intervention types influence the impact of randomized trials in cardiovascular medicine.

Methods

We analyzed late-breaking randomized controlled trials presented at major cardiology conferences from 2015 to 2021. The primary endpoint was the total number of citations obtained. Secondary endpoints included the number of citations at 1 and 2 years, number of total and 1-year mentions, and several metrics of study conduct and publication. Statistical analysis included tests for comparisons of continuous or categorical variable

SUBMITTER: Spagnolo M 

PROVIDER: S-EPMC11344709 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature