Cross-biome microbial networks reveal functional redundancy and suggest genome reduction through functional complementarity.

ABSTRACT: The structure of microbial communities arises from a multitude of factors, including the interactions of microorganisms with each other and with the environment. In this work, we sought to disentangle those drivers by performing a cross-study, cross-biome meta-analysis of microbial occurrence data in more than 5000 samples, applying a novel network clustering algorithm aimed to capture conditional taxa co-occurrences. We then examined the phylogenetic and functional composition of the resulting clusters, and searched for global patterns of assembly both at the community level and in the presence/absence of individual metabolic pathways.Our analysis highlighted the prevalence of functional redundancy in microbial communities, particularly between taxa that co-occur in more than one environm

SUBMITTER: Puente-Sanchez F 

PROVIDER: S-EPMC11344793 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature