Underuse of Postoperative Radiation After Nipple-Sparing Mastectomy for Standard Radiation Indications.

ABSTRACT:

Purpose

Nipple areola complex-sparing surgeries, such as nipple-sparing mastectomy (NSM), are increasingly used for women with early-stage breast cancer. In the postoperative setting, 2 major indications for postoperative radiation (PORT) with/without regional nodal irradiation (RNI) are: positive margins (margin+) and pathologically involved lymph nodes (pN+). The frequency of these adverse pathologic features and the rate of PORT utilization following NSM for these 2 indications are unknown. We determined the frequency of margin+ and pN+ following NSM compared with nipple-sparing lumpectomy/breast-conserving surgery [BCS] and identified trends in appropriate PORT administration for these standard indications in the NSM setting.

Methods and materials

Using the National Canc

SUBMITTER: Talcott WJ 

PROVIDER: S-EPMC11345291 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature