Association between maternal multimorbidity and neurodevelopment of offspring: a prospective birth cohort study from the Japan Environment and Children's Study.

ABSTRACT:

Objectives

To investigate the association between multimorbidity during pregnancy and neurodevelopmental delay in offspring using data from a Japanese nationwide birth cohort study.

Design

This study was a prospective birth cohort study.

Setting

This study population included 104 059 fetal records who participated in The Japan Environment and Children's Study from 2011 to 2014.

Participants

Pregnant women whose children had undergone developmental testing were included in this analysis.

Primary and secondary outcome measures

Neurodevelopment of offspring was assessed using the Japanese version of the Ages and Stages Questionnaire, third edition, comprising five developmental domains. The number of comorbidities among the pregnant women was categorised as

SUBMITTER: Akagi T 

PROVIDER: S-EPMC11345530 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature