Postmenopausal Hormone Therapy Was Associated With Later Age of Onset Among Glaucoma Cases.

ABSTRACT:

Purpose

Hormonal therapy (HT) has been suggested to lower the risk of developing glaucoma. Our goal was to investigate the association between HT use and the onset of glaucoma diagnosis in postmenopausal women.

Methods

This retrospective case-only study included female veterans with open-angle glaucoma from VA records between 2000 to 2019. Propensity score matching was used to match HT (n = 1926) users to untreated (n = 1026) women on multiple covariates (e.g., age of menopause, BMI, blood pressure, antihypertensive medications, and a co-morbidity index). A simple linear regression was used to evaluate the impact of HT duration on the age of glaucoma diagnosis, and multivariate linear regression analysis was used to determine which factors contributed to the age at diagnosis

SUBMITTER: Hogan K 

PROVIDER: S-EPMC11346078 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature