Exposure to household pesticides and Parkinson's disease in the Parkinson's Progression Markers Initiative cohort.

ABSTRACT:

Background

In the last decades, the association of household pesticide usage with Parkinson's disease (PD) has been poorly explored, with discordant results. Based on the Parkinson's Progression Markers Initiative (PPMI) cohort study, we analyzed (1) the association of household pesticide exposure with the development of PD and (2) the effect of household pesticides on progression of PD.

Methods

Data from participants of the "FOllow Up persons with Neurologic Disease" (FOUND study) included in the PPMI cohort database were analyzed. The PPMI FOUND study applied the Parkinson's Disease Risk Factor Questionnaire to collect information regarding the use of pesticides in non-work settings during periods of life, and the lifetime pesticide exposure for each participant was estima

SUBMITTER: Santos-Lobato BL 

PROVIDER: S-EPMC11346339 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature