Sub-10 μm Soft Interlayers Integrating Patterned Multivalent Biomolecular Binding Environments.

ABSTRACT: Designing surfaces that enable controlled presentation of multivalent ligand clusters (e.g., for rapid screening of biomolecular binding constants or design of artificial extracellular matrices) is a cross-cutting challenge in materials and interfacial chemistry. Existing approaches frequently rely on complex building blocks or scaffolds and are often specific to individual substrate chemistries. Thus, an interlayer chemistry that enabled efficient nanometer-scale patterning on a transferrable layer and subsequent integration with other classes of materials could substantially broaden the scope of surfaces available for sensors and wearable electronics. Recently, we have shown that it is possible to assemble nanometer-resolution chemical patterns on substrates including graphite, use diace

SUBMITTER: Nava EK 

PROVIDER: S-EPMC11346468 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature