Emergence and expansion of carbapenem resistant enterobacterales in the Western Cape Province, South Africa.

ABSTRACT:

Background

Carbapenem resistant Enterobacterales (CRE) have become established as leading pathogens in South African healthcare facilities. The aim of this study is to describe the epidemiology of CRE carriage and clinical infection episodes at healthcare facilities in the Western Cape Province of South Africa (2016-2020), and identify factors associated with mortality in CRE infected patients.

Methodology

We used routine data from the Provincial Health Data Centre to track the emergence of CRE in healthcare facilities in the Western Cape Province of South Africa. We included all CRE episodes (clinical and carriage) at Western Cape hospitals (including day and inpatients) from 2016 to 2020 to determine the distribution of CRE, patient demographics and antibiotic resistance p

SUBMITTER: Moloto K 

PROVIDER: S-EPMC11346644 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature