Free-breathing three-dimensional simultaneous myocardial T₁ and T₂ mapping based on multi-parametric SAturation-recovery and Variable-flip-Angle.

ABSTRACT:

Background

Quantitative myocardial tissue characterization with T₁ and T₂ parametric mapping can provide an accurate and complete assessment of tissue abnormalities across a broad range of cardiomyopathies. However, current clinical T₁ and T₂ mapping tools rely predominantly on two-dimensional (2D) breath-hold sequences. Clinical adoption of three-dimensional (3D) techniques is limited by long scan duration. The aim of this study is to develop and validate a time-efficient 3D free-breathing simultaneous T₁ and T₂ mapping sequence using multi-parametric SAturation-recovery and Variable-flip-Angle (mSAVA).

Methods

mSAVA acquires four volumes for simultaneous whole-heart T₁ and T₂ mapping. W

SUBMITTER: Si D 

PROVIDER: S-EPMC11347066 | biostudies-literature | 2024 Winter

REPOSITORIES: biostudies-literature