Mode of delivery predicts postpartum maternal leukocyte telomere length.

ABSTRACT:

Background

Recent studies have suggested that pregnancy accelerates biologic aging, yet little is known about how biomarkers of aging are affected by events during the peripartum period. Given that immune shifts are known to occur following surgery, we explored the relation between mode of delivery and postpartum maternal leukocyte telomere length (LTL), a marker of biologic aging.

Study design

Postpartum maternal blood samples were obtained from a prospective cohort of term, singleton livebirths without hypertensive disorders or peripartum infections between 2012 and 2018. The primary outcome was postpartum LTLs from one blood sample drawn between postpartum week 1 and up to 6 months postpartum, measured from thawed frozen peripheral blood mononuclear cells using quantitati

SUBMITTER: Panelli DM 

PROVIDER: S-EPMC11347108 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature