Impact of repetitive negative thinking on subjective cognitive decline: insights into cognition and brain structure.

ABSTRACT:

Introduction

Individuals with subjective cognitive decline (SCD) express concern about self-perceived cognitive decline despite no objective impairment and are at higher risk of developing Alzheimer's disease. Despite documented links between SCD and repetitive negative thinking (RNT), the specific impact of RNT on brain integrity and cognition in exacerbating the SCD condition remains unclear. We aimed to investigate the influence of RNT on global cognition and brain integrity, and their interrelationships among healthy middle-aged and older adults experiencing SCD.

Methods

Out of 616 individuals with neuroimaging and neuropsychological data available, 89 (mean age = 56.18 years; 68.54% females) met SCD criteria. Eighty-nine non-SCD individuals matched by age, sex, and educ

SUBMITTER: Mulet-Pons L 

PROVIDER: S-EPMC11347316 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature